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Information about Parlodel

Bromocriptine is a dopamine agonist that is used to treat Parkinson disease, certain conditions caused by too much prolactin in the blood (eg, excessive or abnormal breast milk production), certain menstrual problems, or abnormally large growth of certain body parts (acromegaly). It blocks the release of prolactin from the pituitary gland and decreases growth hormone levels (in patients with acromegaly). Also, Bromocriptine stimulates dopamine receptors in certain parts of the brain (in Parkinson disease).

It may also be used for other conditions as determined by your doctor.

You should not use Bromocriptine in case you have any condition mentioned below: you are allergic to any ingredient in Bromocriptine or to ergot alkaloids; you are breast-feeding a baby; you have uncontrolled high blood pressure or developed high blood pressure associated with pregnancy; you have blood poisoning during pregnancy; you have recently given birth and have coronary artery disease (chest pain) or other severe heart disease; you are taking Bromocriptine only for hyperprolactinemia and become pregnant; you are taking an ergot alkaloid (eg, ergotamine), an HIV protease inhibitor (eg, ritonavir), a ketolide (eg, telithromycin), a macrolide (eg, erythromycin), a nonnucleoside reverse transcriptase (NNRT) inhibitor (eg, efavirenz), or sumatriptan.

In such cases it is obligatory to consult with your doctor or health care provider before taking this drug.

Before using Bromocriptine

Before using Bromocriptine you should tell your doctor if you have any medical conditions listed below: you are pregnant or planning to become pregnant; you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement; you have allergies to medicines, foods, or other substances; you have angina (chest pain) or coronary artery disease, irregular heartbeat, high blood pressure, kidney disease, liver disease, mental illness, narrowing of blood vessels of the legs or arms, a history of vision problems, or a history of stomach or intestinal bleeding, or if you have had a heart attack.

Be aware that Bromocriptine may interact with some medicines. Consult with your health care provider in case you are taking any other drugs, especially any of the following: sumatriptan because excessive increases in blood pressure may occur; beta-blockers (eg, propranolol), sympathomimetics (eg, albuterol, amphetamine, pseudoephedrine), ergot alkaloids (eg, ergotamine), HIV protease inhibitors (eg, ritonavir), ketolides (eg, telithromycin), macrolides (eg, erythromycin), medicine for high blood pressure, or NNRT inhibitors (eg, efavirenz) because the risk of side effects of Bromocriptine may be increased; phenothiazines (eg, chlorpromazine), haloperidol, metoclopramide, or pimozide because the effectiveness of Bromocriptine may be decreased; methyldopa because side effects, including dizziness upon standing, may be increased by Bromocriptine.

It may not be a complete list of all interactions with other drugs. To prevent any complications you should check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Bromocriptine

Use this medicine as recommended by your physician. Bromocriptine should be taken with food.

In case you miss a dose of Bromocriptine, take it as soon as possible. If it is almost time for your next intake, skip the missed dose and take it according to your regular dosing schedule. Do not take double doses to catch up.

Important safety information

Be careful when driving, operating machinery, or performing other hazardous activities as Bromocriptine usage may lead to drowsiness, dizziness, or lightheadedness. These conditions may be worsened by alcohol hot weather, exercise, and fever. For the purpose of prevention them, you should sit up or stand slowly, especially in the morning. Also, sit or lie down at the first sign of dizziness, lightheadedness, or weakness. Try to avoid any dangerous activities or any other possibly unsafe tasks while taking Bromocriptine.

Do not give up using Bromocriptine without medical consultation.

Do not stop using Bromocriptine without medical consultation in case you are taking Bromocriptine for a brain tumor. It may lead to rapid regrowth of the tumor.

The effectiveness of your birth control pill may be decreased by Bromocriptine. It is recommended to use an additional form of birth control (eg, condoms) while taking Bromocriptine.

Lab tests, including blood pressure, liver and kidney function, heart function, and blood cell counts, may be performed while you are using Bromocriptine. It is important to control your progress or to check for side effects. Follow all doctor and lab appointments strictly.

You should use Bromocriptine with extreme caution in CHILDREN younger than 15 years of age, as safety and effectiveness in this group have not been proved.

PREGNANCY and BREAST-FEEDING

In case you become pregnant, consult with your doctor and discuss the benefits and risks of taking Bromocriptine while pregnancy. It is clear whether Bromocriptine passes into breast milk. Avoid breast-feeding a baby while using Bromocriptine.

Possible side effects of Bromocriptine

You should consult with your doctor in case you have any of side effects especially bothersome listed below: cold sensitivity in fingers and toes; constipation; diarrhea; dizziness; drowsiness; dry mouth; fatigue; headache; indigestion; lightheadedness; loss of appetite; nausea; stomach cramps; stuffy nose; vomiting.

Seek emergency immediately in case you have any of these severe side effects: severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); abnormal involuntary movements; bloody or black, tarry stools; chest pain; depression; fainting; hallucinations; one-sided weakness; persistent, watery nasal discharge; progressive, severe headache; shortness of breath; ringing in the ears; seizures; slurred speech or trouble speaking; stomach pain; sudden confusion; sudden daytime sleepiness; sudden loss of coordination; vision changes; vomiting blood or a substance like coffee grounds.

What is the expiration date of the pills?

This information is mentioned on each blister. The expiration date is 2 years from the date of manufacture.