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Information about Naprosyn

Naproxen is an NSAID that is used to treat rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, and juvenile arthritis, tendonitis, bursitis, gout, menstrual cramps, or mild to moderate pain. The exact mechanism of Naproxen action is unknown. Probably, it blocks certain substances in the body that are connected with inflammation. NSAIDs help to decrease pain and inflammation.

It may also be used for other conditions as determined by your doctor.

You should not use Naproxen in case you have any condition mentioned below: you are allergic to any ingredient in Naproxen; you have had a severe allergic reaction (eg, severe rash, hives, trouble breathing, growths in the nose, dizziness) to aspirin or a nonsteroidal anti-inflammatory drug (NSAID) (eg, ibuprofen, celecoxib); you have recently had or will be having bypass heart surgery; you are in the last 3 months of pregnancy.

In such cases it is obligatory to consult with your doctor or health care provider before taking this drug.

Before using Naproxen

Before using Naproxen you should tell your doctor if you have any medical conditions listed below: you are pregnant, planning to become pregnant, or are breast-feeding a baby; you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement; you have allergies to medicines, foods, or other substances; you have a history of kidney or liver disease, diabetes, or stomach or bowel problems (eg, bleeding, perforation, ulcers); you have a history of swelling or fluid buildup, asthma, growths in the nose (nasal polyps), or mouth inflammation; you have high blood pressure, blood disorders, bleeding or clotting problems, heart problems (eg, heart failure), or blood vessel disease, or if you are at risk for any of these diseases; you have poor health, dehydration or low fluid volume, or low blood sodium levels, you are on a low salt (sodium) diet, you drink alcohol, or you have a history of alcohol abuse.

Be aware that Naproxen may interact with some medicines. Consult with your health care provider in case you are taking any other drugs, especially any of the following: anticoagulants (eg, warfarin), aspirin, corticosteroids (eg, prednisone), heparin, or selective serotonin reuptake inhibitors (SSRIs) (eg, fluoxetine) because the risk of stomach bleeding may be increased; probenecid because it may increase the risk of Naproxen 's side effects; cyclosporine, hydantoins (eg, phenytoin), lithium, methotrexate, quinolones (eg, ciprofloxacin), sulfonamides (eg, sulfamethoxazole), or sulfonylureas (eg, glipizide) because the risk of their side effects may be increased by Naproxen; angiotensin-converting enzyme (ACE) inhibitors (eg, enalapril), beta-blockers (eg, propranolol), or diuretics (eg, furosemide, hydrochlorothiazide) because their effectiveness may be decreased by Naproxen.

It may not be a complete list of all interactions with other drugs. To prevent any complications you should check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Naproxen

It is recommended to take Naproxen orally. It is better to take it with food in case of stomach upsets. This may not lower the risk of stomach or bowel problems (eg, bleeding, ulcers). Consult with your doctor or pharmacist in case you experience persistent stomach upset.

In case you are taking antacids, cholestyramine, or sucralfate, you should consult with your doctor or pharmacist how to use them with Naproxen. In case you miss a dose of Naproxen, take it as soon as possible. If it is almost time for your next intake, skip the missed dose and take it according to your regular dosing schedule. Do not take double doses to catch up.

Important safety information

Naproxen usage may lead to dizziness or drowsiness. These effects may be worsened by taking alcohol or certain medicines. Prevent driving or performing any other possibly dangerous actions.

Naproxen usage may lead to serious stomach ulcers or bleeding. These effects may be worsened by using Naproxen in high doses, for a long period of time, smoking, or drinking alcohol. Using Naproxen in combination with food will NOT reduce the risk of such effects.

You should know that Naproxen is an NSAID. Before you start any new medicine, check the label whether it contains an NSAID (eg, ibuprofen). In case it does or you are not sure, consult with your doctor or pharmacist.

You should not take aspirin if you are taking Naproxen unless your doctor recommends otherwise.

Lab tests, including kidney function, complete blood cell counts, and blood pressure, may be performed while you are using Naproxen. It is important to control your progress or to check for side effects. Follow all doctor and lab appointments strictly.

The ELDERLY are likely to be more sensitive to its effects, especially stomach bleeding and kidney problems. Use Naproxen with caution in this group.

Use Naproxen with extreme caution in CHILDREN younger than 2 years old as safety and effectiveness in this group have not been proved.

PREGNANCY and BREAST-FEEDING

Naproxen may be deleterious to the fetus. You should not use it during the last 3 months of pregnancy. In case you could become pregnant, consult with your doctor and discuss the benefits and risks of using Naproxen while pregnancy. It is clear that Naproxen passes into breast milk. Avoid breast-feeding a baby while using Naproxen.

Possible side effects of Naproxen

You should consult with your doctor in case you have any of side effects especially bothersome listed below: constipation; diarrhea; dizziness; drowsiness; gas; headache; heartburn; nausea; stomach upset; stuffy nose.

Seek emergency immediately in case you have any of these severe side effects: severe allergic reactions (rash; hives; itching; trouble breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); bloody or black, tarry stools; change in the amount of urine produced; chest pain; confusion; dark urine; depression; fainting; fast or irregular heartbeat; fever, chills, or persistent sore throat; mental or mood changes; numbness of an arm or leg; one-sided weakness; red, swollen, blistered, or peeling skin; ringing in the ears; seizures; severe headache or dizziness; severe or persistent stomach pain or nausea; severe vomiting; shortness of breath; sudden or unexplained weight gain; swelling of hands, legs, or feet; unusual bruising or bleeding; unusual joint or muscle pain; unusual tiredness or weakness; vision or speech changes; vomit that looks like coffee grounds; yellowing of the skin or eyes.

What is the expiration date of the pills?

This information is mentioned on each blister. The expiration date is 2 years from the date of manufacture.