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Information about Imdur

Isosorbide Mononitrate is a nitrate vasodilator that is used for preventing angina (chest pain) that may be caused by heart disease. It widens the blood vessels in the body and decreases the workload of the heart. It helps to relieve chest pain.

You should not use Isosorbide Mononitrate in case you have any condition mentioned below: you are allergic to any ingredient in Isosorbide Mononitrate or to other nitrate medicines; you are also taking a phosphodiesterase type 5 inhibitor (eg, sildenafil, tadalafil, vardenafil); you drink alcohol.

In such cases it is obligatory to consult with your doctor or health care provider before taking this drug.

Before using Isosorbide Mononitrate

Before using Isosorbide Mononitrate you should tell your doctor if you have any medical conditions listed below: you are pregnant, planning to become pregnant, or are breast-feeding a baby; you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement; you have allergies to medicines, foods, or other substances; you have heart problems (eg, heart failure, heart attack, hypertrophic cardiomyopathy), low blood pressure, blood problems (eg, anemia), dehydration, bleeding the brain, an overactive thyroid, or have had a recent head injury.

Be aware that Isosorbide Mononitrate may interact with some medicines. Consult with your health care provider in case you are taking any other drugs, especially any of the following: calcium channel blockers (eg, diltiazem, verapamil) or phosphodiesterase type 5 inhibitors (eg, sildenafil, tadalafil, vardenafil) because the risk of severe low blood pressure may be increased.

It may not be a complete list of all interactions with other drugs. To prevent any complications you should check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Isosorbide Mononitrate

It is recommended to take Isosorbide Mononitrate twice a day (with the doses 7 hours apart) orally with or without food. Take the first dose in the morning upon waking up, unless otherwise recommended by your physician.

Try not to give up using Isosorbide Mononitrate suddenly. It may lead to the development of side effects (eg, angina attacks). It is important to lower your dose gradually.

In case you miss a dose of Isosorbide Mononitrate, take it as soon as possible. If it is almost time for your next intake, skip the missed dose and take it according to your regular dosing schedule. Do not take double doses to catch up.

Important safety information

Isosorbide Mononitrate usage may lead to dizziness or drowsiness. These effects may be worsened by taking alcohol or certain medicines. Prevent driving or performing any other possibly dangerous actions.

Be aware that alcohol, hot weather, exercise, or fever may increase dizziness or lightheadedness while taking Isosorbide Mononitrate. For the purpose of dizziness or lightheadedness prevention, try to sit up or stand slowly, especially in the morning. Sit or lie down at the first sign of any of these effects.

Avoid drinking alcohol while you are using Isosorbide Mononitrate.

You may experience headaches when you begin taking Isosorbide Mononitrate. Consult with your doctor how to reduce this side effect. Isosorbide Mononitrate is not intended to stop an attack of angina; it is intended only for the purpose of prevention.

Certain lab tests may be interfered by Isosorbide Mononitrate usage. Notice doctor and lab personnel that you are using this drug.

Do not use Isosorbide Mononitrate in CHILDREN as safety and effectiveness in children have not been confirmed.

PREGNANCY and BREAST-FEEDING

In case you become pregnant, consult with your doctor and discuss the benefits and risks of taking Isosorbide Mononitrate while pregnancy. It is not clear whether Isosorbide Mononitrate passes into breast milk. In case you are or will be breast-feeding a baby while you take Isosorbide Mononitrate, consult with your doctor and discuss any possible risks to your baby.

Possible side effects of Isosorbide Mononitrate

You should consult with your doctor in case you have any of side effects especially bothersome listed below: dizziness; headache; nausea.

Seek emergency immediately in case you have any of these severe side effects: severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); changes in vision; fainting; numbness of an arm or leg; severe stomach pain; sharp or crushing chest pain; sudden leg pain; sudden, severe headache; sudden shortness of breath; vomiting.

What is the expiration date of the pills?

This information is mentioned on each blister. The expiration date is 2 years from the date of manufacture.