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Generic HydreaCancer / Generic Hydrea
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Information about Hydrea

Hydroxyurea is an antineoplastic agent that is taken for reducing the number of painful episodes and blood transfusions needed by adults with sickle cell anemia experiencing recurrent episodes associated with moderate to severe pain. Hydroxyurea may be administered to treat other conditions as determined by your physician. The exact mechanism of action is unknown. Hydroxyurea is likely to increase the ability of deformed red blood cells to change shape, which may decrease pain associated with sickle cell anemia.

You should not use Hydroxyurea if you are allergic to any components in it or you have severe bone marrow depression, low white blood cell counts, low blood platelet levels, or severe anemia. In such cases it is obligatory to consult with your doctor or health care provider before taking this medicine.

Before using Hydroxyurea you should tell your doctor if you have any medical conditions, or if you are pregnant, planning to become pregnant, or are breastfeeding a baby, if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement, if you have allergies to medicines, foods, or other substances, if you have kidney problems.

Be aware that Hydroxyurea may interact with some medicines. Consult with your health care provider in case you are taking any other drugs, especially any of the next: Didanosine because the risk of side effects such as inflammation of the pancreas may be increased.

It may not be a complete list of all interactions with other drugs. To prevent any complications you should check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Hydroxyurea

You should use Hydroxyurea as recommended by your doctor with or without food. In case you have difficulty swallowing, empty the contents of the capsule into a glass of water and drink immediately. Use care when emptying the capsule. Try to avoid the contact of powder with the skin or mucous membranes and do not breathe in the powder. In case the powder is spilled, wipe it up immediately with a damp towel and disposed of, as should the empty capsules. Wash your hands before and after handling Hydroxyurea.

Read the additional patient leaflet carefully and reread it each time you get Hydroxyurea refilled.

Drinking extra fluids is recommended while using Hydroxyurea. For extra information consult with your doctor.

It is banned to use Hydroxyurea if the expiration date has passed.

In case you miss a dose, take it as soon as possible. If it is almost time for your next intake, skip the missed dose and take it according to your regular schedule. Do not take double doses at once. You should ask your health care provider if you have any questions about usage of Hydroxyurea.

Important safety information

You should consult with your doctor in case you are going to have any medical or dental treatments, emergency care, or surgery, tell the doctor or dentist that you are using Hydroxyurea.

You should know that Hydroxyurea may decrease your body's ability to fight infection. Try to avoid contacts with people with colds or other infections. Tell your doctor if you have any signs of infection (fever, sore throat, rash, or chills).

The quantity of clot-forming cells (platelets) in blood may be decreased while taking Hydroxyurea. Try to prevent situations in which bruising or injury may occur. Tell your doctor if you have unusual bleeding, bruising, blood in stools, or dark, tarry stools.

Vaccinations with live virus vaccines (eg, measles, mumps, oral polio) should be avoided while you are taking Hydroxyurea because it may be less effective.

To monitor your progress or to check for side effects lab tests , including complete blood cell and platelet counts, may be performed. Follow all doctor and lab appointments strictly.

Elderly people are likely to be more sensitive to Hydroxyurea. It is not recommended for use in children.

It was shown that Hydroxyurea is harmful to the fetus. It is not allowed to use Hydroxyurea in case you are pregnant or breast-feeding a baby. It is known that Hydroxyurea passes into breast milk. If you become pregnant, consult with your doctor the benefits and risks.

Possible side effects of Hydroxyurea

You should consult with your doctor if you have any of side effects especially bothersome listed below: Constipation; drowsiness; hair loss; inflammation of the mouth; loss of appetite; nausea; redness of the face.

Seek emergency in case you have any of these severe side effects

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); blood disorders, including low numbers of red or white blood cells; blood in the urine; chills; diarrhea; fever; inflammation of the pancreas; liver toxicity; lower back or abdominal pain; painful urination; persistent cough; secondary leukemia; shortness of breath; skin cancer; skin sore or lesions; sore throat; sores on the mouth or lips; unusual bruising or bleeding; vomiting.

What is the expiration date of the pills?

This information is mentioned on each blister. The expiration date is 2 years from the date of manufacture.

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