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Information about Cordarone

Amiodarone is in the class of antiarrhythmics. It effects by stabilizing the heart rhythm in conditions in which the patient suffers too fast heart beating or an irregular rhythm. It is usually used in situations in which the abnormal heart rhythms that could cause death in case it is not treated. It may also be used for other conditions as prescribed by your doctor.

You should not use Amiodarone in case you are allergic to any ingredient in Amiodarone or iodine; you experience complete, second degree, third degree, or severe sinoatrial heart block; an abnormally slow heartbeat; or shock because of serious heart problems; or if you have a history of fainting because of slow heartbeat (except if you have a pacemaker); you are administering cisapride, dofetilide, an H1 antagonist (eg, astemizole, loratadine, terfenadine), an HIV protease inhibitor (eg, ritonavir), a phosphodiesterase type 5 inhibitors (eg, vardenafil), or a streptogramin (eg, dalfopristin, quinupristin) In such cases it is obligatory to consult with your doctor before taking this medicine.

Before using Amiodarone

Be aware that Amiodarone may interact with some medical conditions. Consult with your doctor in case you have any medical conditions listed below: if you are pregnant, planning to become pregnant, or are breast-feeding; if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement; if you have allergies to medicines, foods, or other substances; if you have a history of liver problems, lung disease, heart problems, low blood pressure, thyroid problems, electrolyte problems (eg, low blood potassium or magnesium), eye problems, or sinoatrial heart block; if you are going surgery; if you take medicine for diabetes (eg, glyburide).

Be aware that Amiodarone may interact with some medicines. Consult with your doctor in case you are taking any other medicines, especially any of the next: Cholestyramine, hydantoins (eg, phenytoin), rifampin, or St. John's wort because they may decrease Amiodarone 's effectiveness; Antiarrhythmics (eg, flecainide), arsenic, azole antifungals (eg, ketoconazole), cimetidine, cisapride, diuretics (eg, furosemide, hydrochlorothiazide), dofetilide, droperidol, H1 antagonists (eg, astemizole, loratadine, terfenadine), HIV protease inhibitors (eg, ritonavir), ketolides (eg, telithromycin), macrolide antibiotics (eg, erythromycin), phenothiazines (eg, thioridazine), phosphodiesterase type 5 inhibitors (eg, vardenafil), pimozide, quinolones (eg, ciprofloxacin), serotonin receptor antagonists (eg, dolasetron), streptogramins (eg, dalfopristin, quinupristin), trazodone, or ziprasidone because side effects, such as heart rhythm problems or seizures, may occur; Narcotic pain relievers (eg, fentanyl) because low blood pressure, slow heartbeat, and other heart problems may occur; Anticoagulants (eg, warfarin), beta-blockers (eg, propranolol), calcium channel blockers (eg, verapamil, diltiazem), cyclosporine, dextromethorphan, digoxin, HMG-CoA reductase inhibitors (eg, simvastatin), lidocaine, or methotrexate because their actions and side effects may be increased by Amiodarone; Thyroid hormones (eg, levothyroxine) because their effectiveness may be decreased or their risk of side effects may be increased by Amiodarone; Clopidogrel because its effectiveness may be decreased by Amiodarone.

This may not be a complete list of all interactions with other drugs. To prevent any complications you should check with your doctor before you start, stop, or change the dose of any medicine.

How to use Amiodarone

Take Amiodarone according to the prescription of your doctor. Amiodarone is to be orally taken with food, as it improves the absorption of this medicine. However you may take Amiodarone on an empty stomach. Choose one way of administering (with food or on an empty stomach).

Do not eat grapefruit or drink grapefruit juice during the treatment with Amiodarone.

Take Amiodarone at the same time each day. This helps Amiodarone to work better.

You should take the missed dose as soon as you remember and then follow your usual schedule. Nevertheless, if it is near to the time for your next dose, do not take an extra tablet to catch up for the dose you forgot. Wait and take your next tablet at the regular time. Do not take a double dose. Ask your doctor for extra information about Amiodarone usage.

Important safety information

Amiodarone may cause dizziness, lightheadedness, or blurred vision, so be careful when driving, operating machinery, or performing other hazardous activities. You should avoid such activities if you experience dizziness, lightheadedness, or blurred vision. Alcohol may increase such symptoms. Avoid taking alcohol and other medicines.

You may experience blue-gray discoloration of the skin, particularly of the face and hands after long-term exposure to Amiodarone. These symptoms are not dangerous and disappear after the treatment is over. Try not to expose to the sun, sunlamps, or tanning booths. You may feel better only in several days or even up to 3 weeks after you have started the treatment.

Be careful not only when you are taking Amiodarone, but for several months after treatment with Amiodarone has stopped if you need to take other medicines.

You may become sensitive to the sun while taking Amiodarone. If you do not know your reaction to Ramipril, try not to expose to the sun, sunlamps, or tanning booths. Wear a sunscreen or protective clothing if you go out. Let your doctor or dentist know that you take Amiodarone before you receive any medical or dental care, emergency care, or surgery.

Do check your pulse rate every day while you take Amiodarone.

Do always carry an identification card that says you are taking Amiodarone.

LAB TESTS, including electrocardiogram (ECG), chest x-rays, lung tests, liver tests, thyroid tests, and eye exams may be performed to monitor your progress.

Use Amiodarone in CHILDREN with caution; there is no reliable data about safety and effectiveness in children.

PREGNANCY and BREAST-FEEDING

Consult with your doctor if you plan to become pregnant, as the benefits and risks of using Amiodarone during while you are pregnant are not known. There is no reliable data whether Amiodarone passes into breast milk. You are not recommended to breast-feed when being treated with Amiodarone.

Possible side effects of Amiodarone

Not everyone experience side effects, however consult with your doctor if you have any of the most COMMON side effects: Abnormal skin sensations (loss of sensation; tingling; numbness; prickling); bitter taste in mouth; blue-green discoloring of skin (especially hands or feet); constipation; decreased sexual interest; dizziness; dry eyes; flushing of the face; general body discomfort; headache; involuntary muscle movements; loss of appetite; nausea; poor coordination; tiredness; trouble sleeping; vomiting. Seek emergency if you experience any sever side effect: Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); chest pain; chills, coldness; cough; coughing up blood; dark urine; decreased urination; easy bruising or bleeding; enlarged thyroid gland; eye discomfort; fatigue; fever; irregular pulse; loss of coordination; menstrual changes; muscle pain, tenderness, or weakness (especially with fever or unusual tiredness); nervousness; persistent sore throat; severe dizziness; severe stomach pain; shortness of breath; skin reaction similar to serious sunburn; slow heartbeat; sluggishness; sweating; tingling or numbness of hands or feet; uncontrolled shaking or tremor; unexplained weight change; vision changes (seeing halos, blurred vision, loss of vision); wheezing; worsening of irregular heartbeat; yellowing of the skin or eyes.

What is the expiration date of the pills?

This information is mentioned on each blister. The expiration date is 2 years from the date of manufacture.